Selenium (Se)

Tiny Nutrient for Immunity and Cell Health

Selenium is a trace element that packs a powerful punch for your health, protecting your cells and boosting your immune system. Found in foods like Brazil nuts, fish, and eggs, it’s a nutrient you need in small amounts to stay vibrant. Whether you’re aiming for stronger immunity, healthier skin, or a balanced thyroid, understanding selenium can help you make smart choices for your wellness. Let’s explore why this unsung hero matters and how to keep it balanced for a thriving you.

Chemical Identity and Role

Selenium (Se) is a non-metal element, number 34 on the periodic table, with a shiny, gray appearance. In your body, it’s a trace element, needed in micrograms and found mostly in the liver, kidneys, and muscles. Selenium is a key component of selenoproteins, special proteins that act as antioxidants and support thyroid and immune function. It’s essential for protecting cells and keeping your systems in harmony.

Biological Role and Health Impact

Selenium is a multitasking nutrient with big benefits:

  • Cell Protection: As part of antioxidant enzymes (like glutathione peroxidase), selenium shields cells from damage caused by stress, pollution, or aging.
  • Immune Support: It boosts white blood cell activity, helping your body fight infections and possibly reducing inflammation.
  • Thyroid Health: Selenium helps produce and regulate thyroid hormones, which control metabolism, energy, and mood.
  • Heart Health: It may lower heart disease risk by reducing oxidative stress and improving cholesterol levels.
  • Brain Function: Selenium supports cognitive health, potentially reducing risks of mood disorders or cognitive decline.
  • Fertility and Reproduction: It aids sperm production and may support healthy pregnancy outcomes.

Research links adequate selenium to stronger immunity, better thyroid function, and lower risks of certain cancers, though more studies are needed for cancer prevention claims.

Sources (Dietary or Environmental)

Selenium is found in small amounts in many foods, with levels varying by soil content:

  • Dietary Sources:
    • Nuts and Seeds: Brazil nuts (1 nut, ~68–91 mcg), sunflower seeds (1 oz, ~14 mcg).
    • Seafood: Tuna (3 oz, ~92 mcg), shrimp (3 oz, ~40 mcg), salmon (3 oz, ~38 mcg).
    • Meat and Poultry: Beef (3 oz, ~33 mcg), chicken (3 oz, ~22 mcg), turkey (3 oz, ~31 mcg).
    • Eggs and Dairy: Eggs (1 large, ~15 mcg), cottage cheese (½ cup, ~12 mcg).
    • Grains and Veggies: Brown rice (1 cup cooked, ~19 mcg), spinach (1 cup cooked, ~11 mcg).
  • Environmental Sources:
    • Selenium is naturally in soil, absorbed by plants and animals, but levels vary by region (e.g., high in U.S., low in parts of China).
    • Drinking water contains negligible amounts (<0.01 mcg per liter).
  • Supplemental Sources:
    • Selenomethionine or sodium selenite in multivitamins or standalone supplements (20–200 mcg per dose).
    • Often marketed for immunity or thyroid support, but diet usually suffices.

A varied diet with nuts, seafood, or grains typically meets selenium needs.

Deficiency/Excess Signs

Selenium imbalances are rare but can affect health, especially in specific regions or groups:

  • Deficiency Signs:
    • Fatigue, muscle weakness, or hair loss.
    • Weakened immunity, leading to frequent infections.
    • Thyroid issues (e.g., hypothyroidism), causing weight gain or low energy.
    • Deficiency is rare in the U.S. but more common in low-selenium soil areas (e.g., parts of China) or with poor diets (e.g., vegan without nuts).
  • Excess Signs:
    • Brittle nails, hair loss, or garlic-like breath odor (from doses >400 mcg/day).
    • Nausea, diarrhea, or skin rashes.
    • Neurological issues like tremors or confusion (in severe cases, >1,000 mcg/day).
    • Excess is rare from food but possible from supplements or eating too many Brazil nuts (e.g., 10+ daily).

Blood tests can check selenium levels if you’re at risk (e.g., thyroid issues or low intake).

Supporting Optimal Levels

You can optimize selenium’s benefits with these practical tips:

  • Eat Selenium-Rich Foods: Include 1–2 servings weekly of Brazil nuts (1–2 nuts), fish, or eggs to meet needs naturally.
  • Balance Your Diet: Pair with vitamin E (e.g., almonds, spinach) and iodine (e.g., seafood, iodized salt) to support antioxidant and thyroid function.
  • Limit Brazil Nuts: Stick to 1–2 daily to avoid excess, as they’re extremely high in selenium.
  • Stay Active: Exercise (e.g., 150 minutes of walking or yoga weekly) supports immunity and metabolism, where selenium shines.
  • Use Supplements Cautiously: If deficient (e.g., vegan or low-soil area), 50–100 mcg daily is enough—consult a doctor, as excess can harm.
  • Check Soil Region: If you live in a low-selenium area (rare in the U.S.), rely on seafood, nuts, or fortified foods.
  • Monitor Thyroid Health: If you have thyroid issues, ensure adequate selenium and iodine, but avoid high doses without medical guidance.

Adults need 55 mcg daily (70 mcg for pregnant/breastfeeding women), with an upper limit of 400 mcg to avoid toxicity.

Safety, Interactions, and Precautions

Selenium is safe in dietary amounts but needs caution with supplements:

  • Interactions:
    • Medications: Selenium may interact with chemotherapy drugs or statins—consult a doctor if on these treatments.
    • Iodine: Selenium and iodine work together for thyroid health; deficiency or excess in one can affect the other.
    • Antioxidants: Works with vitamins C and E to protect cells—include these in your diet.
  • Precautions:
    • People with thyroid disorders (e.g., Hashimoto’s) should avoid high doses, as excess selenium can worsen symptoms.
    • Those in low-selenium regions or on restrictive diets (e.g., vegan without nuts) may need dietary or supplemental boosts.
    • Avoid high-dose supplements (>400 mcg/day) unless prescribed, as they can cause toxicity (selenosis).
    • Environmental selenium (e.g., in contaminated soil or water) is rare but can increase risk—use clean water sources.
  • Who’s at Risk? Vegans, those in low-selenium regions, or with thyroid issues need extra attention to selenium balance.

Fun Fact

Selenium is a lunar element! It’s named after the Greek word “selene,” meaning moon, due to its silvery shine. In your body, it’s a shining star, protecting your cells and keeping your thyroid glowing with health!

Citations

  1. National Institutes of Health. (2025). Selenium: Fact Sheet for Health Professionals. Office of Dietary Supplements.
  2. Mayo Clinic. (2024). Selenium: Benefits and Risks for Health.
  3. Cleveland Clinic. (2023). Selenium and Your Thyroid: What You Need to Know.
  4. USDA FoodData Central. (2025). Nutrient Database for Selenium Content in Foods.
  5. World Health Organization. (2022). Trace Elements in Human Nutrition and Health.